Jake Neumann, Ph.D.

Jake Neumann, Ph.D.
Assistant Professor of Pharmacology
Biomedical Sciences

Email: JNeumann@osteo.wvsom.edu
Office: A315
Lab: 217 Science Building
Phone: (304) 793-6236
Fax: (304) 793-6884


Education / Training

Ph.D., Pharmacology, Southern Illinois University School of Medicine

Postdoctoral training, University of Miami Miller School of Medicine

Research Interests

Currently, my lab is studying hippocampal neuronal damage following cerebral ischemia and various mechanism for neuroprotection.

Our interests including understanding how excitatory and inhibitory neurotransmission is altered following ischemia, investigating various methods to improve synaptic signaling for functional recovery, and identifying pharmacological agents for neuroprotection.

Research publications, peer reviewed:

  1. Koronowski KB, Dave KR, Saul I, Camarena V, Thompson JW, Neumann JT, Young JI, Perez-Pinzon MA. Resveratrol Preconditioning Induces a Novel Extended Window of Ischemic Tolerance in the Mouse Brain. Stroke. 2015 Jul 9.
  2. Cohan CH, Neumann JT, Dave KR, Alekseyenko A, Binkert M, Stransky K, Lin HW, Barnes CA, Wright CB, Perez-Pinzon MA. Effect of cardiac arrest on cognitive impairment and hippocampal plasticity in middle-aged rats. PLoS One. 2015 May 1;10(5):e0124918. doi: 10.1371/journal.pone.0124918. eCollection 2015. PubMed PMID: 25933411.
  3. Neumann JT, Thompson JW, Raval AP, Cohan CH, Koronowski KB, Perez-Pinzon MA. Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection. J Cereb Blood Flow Metab. 2015 Jan;35(1):121-30. doi: 10.1038/jcbfm.2014.185. Epub 2014 Nov 5. PubMed PMID: 25370861.
  4. Morris-Blanco KC, Cohan CH, Neumann JT, Sick TJ, Perez-Pinzon MA. Protein kinase C epsilon regulates mitochondrial pools of Nampt and NAD following resveratrol and ischemic preconditioning in the rat cortex. J Cereb Blood Flow Metab. 2014 Jun;34(6):1024-32. doi: 10.1038/jcbfm.2014.51. Epub 2014 Mar 26. PubMed PMID: 24667915.
  5. Lin HW, Gresia VL, Stradecki HM, Alekseyenko A, Dezfulian C, Neumann JT, Dave KR, Perez-Pinzon MA. Protein kinase C delta modulates endothelial nitric oxide synthase after cardiac arrest. J Cereb Blood Flow Metab. 2014 Apr;34(4):613-20. doi: 10.1038/jcbfm.2013.232. Epub 2014 Jan 22. PubMed PMID: 24447953.
  6. Lin HW, Saul I, Gresia VL, Neumann JT, Dave KR, Perez-Pinzon MA. Fatty acid methyl esters and Solutol HS 15 confer neuroprotection after focal and global cerebral ischemia. Transl Stroke Res. 2014 Feb;5(1):109-17. doi: 10.1007/s12975-013-0276-z. Epub 2013 Aug 6. PubMed PMID: 24323706.
  7. Neumann JT, Cohan CH, Dave KR, Wright CB, Perez-Pinzon MA. Global cerebral ischemia: synaptic and cognitive dysfunction. Curr Drug Targets. 2013 Jan 1;14(1):20-35. Review. PubMed PMID: 23170794.

For a full list please go to: