Untitled Document

Gabor Szalai, Ph.D.

Gabor Szalai, Ph.D.
Associate Professor of Immunology
Biomedical Sciences

Office: A328 Main building
Email: gszalai@osteo.wvsom.edu
Office: (304) 647-6370
Fax: (304) 793-6884

 

Education / Training

Ph.D. Immunogenetics, Technical University of Budapest, Budapest, Hungary

M.Sc. Biological Engineering, Technical University of Budapest, Budapest, Hungary

B.Sc. Chemical Engineering, Technical University of Budapest, Budapest, Hungary

Research Interests

My goal is to use the Peromyscus audiogenic seizure susceptible animals for developing a novel model to study the genetic cause, development and progression of epilepsy. The short-term projects of my research are:

  1. behavioral characterization using state-of-the-art sound generating and monitoring equipment to identify acoustic stimulus parameters that trigger a seizure
  2. genetic fine mapping of the ‘epl’ mutation in Peromyscus animals

The long-term aim of the work is to provide a well defined, natural epilepsy model that will allow to test potential anticonvulsants, study the effect of natural genetic variation on disease outcome, etc.

Selected Scholarly Activity

Szántó-Egész, R.; Jánosi, A.; Mohr, A.; Szalai, G.; Szabó, E. Koppányné; Micsinai, A.; Sipos, R.; Rátky, J.; Anton, I.; Zsolnai, A.: Breed-Specific Detection of Mangalica Meat in Food Products. Food Analytical Methods 9(4): 889–894, 2016.

Wiedmeyer CE, Crossland JP,Veres M, Dewey MJ, Felder MR, Barlow SC, Vrana PB, Szalai G: Comparative Hematological and Serum Biochemical Values among Peromyscus Species  and Their Hybrids. J Am Assoc Lab Anim Sci, 53(4):336-43, 2014.

Crossland JP, Dewey MJ, Barlow SC, Vrana PB, Felder MR and Szalai G: Caring for Peromyscus spp. in research environments. Lab Animal 43(5): 162-166, 2014.

Kenney-Hunt J, Lewandowski A, Glenn TC, Glenn JL, Tsyusko OV, O'Neill RJ, Brown J, Ramsdell CM, Nguyen Q, Phan T, Shorter KR, Dewey MJ, Szalai G, Vrana PB, Felder MR.: A genetic map of Peromyscus with chromosomal assignment of linkage groups (a Peromyscus genetic map). Mamm Genome 25(3-4):160-79, 2014.

Vrana PB, Shorter KR, Szalai G, Felder MR, Crossland JP, Veres M, Allen JE, Wiley CD, Duselis AR, Dewey MJ, Dawson WD.: Peromyscus (deer mice) as developmental models. Wiley Interdiscip Rev Dev Biol. 3(3):211-30, 2014.

Tucsek Z, Toth P, Sosnowska D, Gautam T, Mitschelen M, Koller A, Szalai G, Sonntag WE, Ungvari Z, and Csiszar A.:Obesity in Aging Exacerbates Blood-Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer's Disease. J Gerontol A Biol Sci Med Sci. 69(10):1212-26, 2014.

Szalai G, Payne S, Veres M, Fernandes P and Crossland JP: Equipment to induce audiogenic seizures in deer mice. Lab Animal 42(5):165-169, 2013.

Jašarević E, Bailey DH, Crossland JP, Dawson WD, Szalai G, Ellersieck MR, Rosenfeld CS and Geary DC: Evolution of Monogamy, Paternal Investment, and Female Life History in Peromyscus. J Comp Psychol. . 127(1):91-102, 2013.

Shorter K, Crossland J, Webb D, Szalai G, Felder MR and Vrana PB: Peromyscus as a Mammalian Epigenetic Model. Genetics Research International 2012: Article ID 179159, 2012.

Veres M, Duselis AR, Graft A, Pryor W, Crossland J, Vrana PB and Szalai G.:The biology and methodology of assisted reproduction in deer mice (Peromyscus maniculatus). Theriogenology 77: 311-319, 2012.

Findlay VJ, Turner DP, Yordy JS, McCarragher B, Shriver MR, Szalai G, Watson PM, Larue AC, Moussa O, Watson DK: Prostate-Derived ETS Factor Regulates Epithelial-to-Mesenchymal Transition through Both SLUG-Dependent and Independent Mechanisms. Genes & Cancer 2(2):120-9, 2011.

Yang G, Veres M, Szalai G, Zhang A, Xu LX and He X.: Biotransport Phenomena in Freezing Mammalian Oocytes. Annals of Biomedical Engineering 39(1):580-91, 2011.

Asano Y, Stawski L, Hant F, Highland K, Silver R, Szalai G, Watson DK, Trojanowska M.: Endothelial Fli1 deficiency impairs vascular homeostasis: a role in scleroderma vasculopathy. American Journal of Pathology. 176(4):1983-98, 2010.

Ryan, K and Szalai G: A Model for Understanding Epilepsy in Peromyscus. Journal of the  South Carolina Academy of Sciences. 8(1):14-20, 2010.

Csiszar A, Labinskyy N, Mukhopadhyay P, Toth J, Szalai G, Veres M, Pacher P, Podlutsky A, Austad S, Ungvari Z: Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in P. leucopus. American Journal of  Physiology Heart and Circulation Physiology,296(4):H946-5, 2009.

*For a full list go to https://www.researchgate.net/profile/Gabor_Szalai